Lung Edema Clearance: 20 Years of Progress Selected Contribution: Mechanisms that may stimulate the resolution of alveolar edema in the transplanted human lung
نویسندگان
چکیده
LORRAINE B. WARE,1 XIOHUI FANG,2 YIBING WANG,2 TSUTOMU SAKUMA,3 TIMOTHY S. HALL,4 AND MICHAEL A. MATTHAY2,5 1Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2650; 2Cardiovascular Research Institute, University of California, San Francisco, California 94143-0130; 3Thoracic Surgery, Kanazawa Medical University, Kanazawa, Japan 920-02; 4Department of Surgery and Cardiothoracic Transplantation 94143, and 5Departments of Medicine and Anesthesia, University of California, San Francisco, California 94143-0624
منابع مشابه
Selected contribution: mechanisms that may stimulate the resolution of alveolar edema in the transplanted human lung.
Pulmonary edema is common in organ donors and lung transplant recipients. Therefore, we assessed the responsiveness of human donor lungs to pharmacological agents that stimulate clearance of alveolar edema. Organ donors whose lungs were rejected for transplantation were studied. After resection, transport (4 degrees C), and rewarming (37 degrees C) of lungs, alveolar fluid clearance was measure...
متن کاملMathematical Modelling of Pulmonary Edema
The excess accumulation of water in lung interstitial or alveolar is called pulmonary edema which is caused by factors that upset the normal Starling balance in micro-circulation. Pulmonary edema disturbs the alveolar gas exchanges which are normally regulated by the respiratory system. Mathematical modelling of pulmonary edema may help to predict the lung conditions and the mechanisms involved...
متن کاملMathematical Modelling of Pulmonary Edema
The excess accumulation of water in lung interstitial or alveolar is called pulmonary edema which is caused by factors that upset the normal Starling balance in micro-circulation. Pulmonary edema disturbs the alveolar gas exchanges which are normally regulated by the respiratory system. Mathematical modelling of pulmonary edema may help to predict the lung conditions and the mechanisms involved...
متن کاملLung edema clearance: 20 years of progress.
This year marks the 20th anniversary of the publication of a landmark paper by Dr. Michael Matthay and colleagues in the Journal of Applied Physiology that proved to be pivotal in the study of lung edema clearance. To honor this achievement, I am pleased to introduce the newest Highlighted Topics series entitled, “Lung Edema Clearance: 20 Years of Progress.” In addition to featuring original re...
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Sznajder, J. I., P. Factor, and D. H. Ingbar. Invited Review: Lung edema clearance: role of Na -K -ATPase. J Appl Physiol 93: 1860–1866, 2002. 10.1152/japplphysiol.00022.2002.—Acute hypoxemic respiratory failure is a consequence of edema accumulation due to elevation of pulmonary capillary pressures and/or increases in permeability of the alveolocapillary barrier. It has been recognized that lu...
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